How patients and families respond to Alzheimer's biomarker-informed diagnoses
Official title: Patient and Family Member Reactions to Biomarker-Informed ADRD Diagnoses
Funded at University of California at Davis · NIH-11481549 · Data updated 2026-11-12
This project follows people getting Alzheimer’s biomarker results and their close family members to track how the information affects feelings and decisions over six months.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | March 1, 2023 |
| Project end | February 28, 2028 |
| Funding year | 2026 |
| Award (this year) | $597,287 |
| NIH project number | 4R01AG080591-03 |
| Project ID | NIH-11481549 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults undergoing Alzheimer’s biomarker testing who have cognitive symptoms and their immediate family members, able to take part remotely for six months, are ideal candidates.
✕Less likely to help
People not undergoing biomarker testing, those without cognitive concerns, or those unable to participate remotely are unlikely to get direct benefit from this project.
What this research studies
If you join, you would be one of 500 people who are already having Alzheimer’s biomarker testing in clinics or research programs across the United States. Participation is remote and lasts six months, with surveys and interviews about emotions, understanding, planning, and family impact after learning biomarker information. The team will look for patterns in emotional responses and link them to clinical and demographic factors. They will also measure how symptomatic patients and their immediate family members value knowing biomarker status.
Why it matters
Potential benefit: Results could help clinicians give better counseling and tailor disclosure and support so patients and families handle biomarker information more safely and usefully.
How similar studies have gone: Prior studies with highly selected, well-educated volunteers generally found that disclosure did not cause major depression or anxiety, but community-based and symptomatic populations have been less studied.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Lingler, Jennifer Hagerty — University of California at Davis
- Study coordinator: Lingler, Jennifer Hagerty
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.