How parasitoid venom proteins affect cell signaling
Regulation of Host Signaling by Parasitoid Venom Proteins
['FUNDING_OTHER'] · OREGON STATE UNIVERSITY · NIH-10654581
This study is looking at how proteins from wasp venom can change how cells in fruit flies communicate, which might help us understand similar processes in humans and how they relate to certain diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON STATE UNIVERSITY (nih funded) |
| Locations | 1 site (CORVALLIS, UNITED STATES) |
| Trial ID | NIH-10654581 on ClinicalTrials.gov |
What this research studies
This research investigates how venom proteins from parasitoid wasps can manipulate the signaling processes within host cells, using the fruit fly Drosophila as a model organism. By examining the interactions between these venom proteins and the host's cellular signaling pathways, the research aims to uncover new mechanisms that regulate cell function. This could provide insights into how similar processes might occur in humans, particularly in the context of diseases caused by deregulated signaling. The approach involves detailed analysis of the effects of these proteins on various cellular processes and signaling systems.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cellular signaling dysfunction, such as certain cancers or metabolic disorders.
Not a fit: Patients with conditions unrelated to cellular signaling or those who do not have a significant immune response may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for understanding and potentially treating diseases linked to disrupted cellular signaling.
How similar studies have performed: Other research has shown success in using model organisms to understand complex signaling mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
CORVALLIS, UNITED STATES
- OREGON STATE UNIVERSITY — CORVALLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MORTIMER, NATHAN TERRY — OREGON STATE UNIVERSITY
- Study coordinator: MORTIMER, NATHAN TERRY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.