How pandemic disruptions to friendships and social life affected teens' brains and emotions

Effects of pandemic-related disruption to social connectedness on the brain and emotional wellbeing in adolescents

NIH-funded research Laureate Institute for Brain Research · NIH-11240278

This project looks at how COVID-related changes in friendships and social contact affected teenagers' brain development and emotional well-being using data collected before, during, and after the pandemic.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionLaureate Institute for Brain Research NIH-funded
Lab location1 site (Tulsa, United States)
Project IDNIH-11240278 on NIH RePORTER

What this research studies

If you're a teen or parent, this work uses long-term data from the Adolescent Brain Cognitive Development (ABCD) study to compare brain scans, surveys, and location-based measures from before, during, and after the pandemic. Researchers link changes in social connectedness (like school closures or reduced time with friends) to emotional symptoms and brain development over time. They also look for pre-existing social or biological factors that made some teens more sensitive to those disruptions. The goal is to understand who struggled most and why so we can better support teens after major social interruptions.

Who could benefit from this research

Good fit: Teenagers roughly aged 12–20 who experienced changes in social contact or routines during the COVID pandemic (especially ABCD study participants) would be the main focus.

Not a fit: Younger children, adults, or teens whose concerns are unrelated to social connectedness or who did not experience pandemic-related social changes are less likely to benefit directly.

Why it matters

Potential benefit: The findings could help identify teens at higher risk for lasting emotional or brain-development effects after social disruption and guide targeted supports or interventions.

How similar studies have performed: Previous work has shown links between isolation and mood symptoms and some ABCD analyses examined pandemic impacts, but combining long-term brain imaging, surveys, and geolocation data for this question is relatively new.

Where this research is happening

Tulsa, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.