How pain medication affects exercise and muscle growth in people with low back pain

The interaction between analgesic medication and exercise-induced musclehypertrophy in patients with low back pain

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10899477

This study is looking at how pain medications work with exercise to help people with chronic low back pain build muscle and recover better, so if you're dealing with this condition, your participation could help improve treatment options for you and others.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded)
Locations1 site (LA JOLLA, UNITED STATES)
Trial IDNIH-10899477 on ClinicalTrials.gov

What this research studies

This research investigates how analgesic medications interact with exercise to influence muscle growth in patients suffering from chronic low back pain. It aims to understand the patterns of medication use and how these medications may affect the effectiveness of exercise-based rehabilitation programs. By examining the relationship between medication, psychosocial factors, and clinical outcomes, the study seeks to provide insights that could improve treatment strategies for individuals with low back pain. Participants will be monitored during their rehabilitation to assess the impact of their medication on muscle adaptation and overall recovery.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing chronic low back pain who are currently undergoing or considering exercise-based rehabilitation.

Not a fit: Patients who do not have chronic low back pain or those not engaged in exercise-based rehabilitation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment plans that enhance recovery and improve quality of life for patients with low back pain.

How similar studies have performed: Previous research has indicated that the interaction between medications and exercise can significantly affect recovery outcomes, suggesting that this study's approach is both relevant and necessary.

Where this research is happening

LA JOLLA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.