How oxytocin helps with pain recovery after nerve injury

Central oxytocin mechanisms of pain recovery following nerve injury

NIH-funded research Wake Forest University Health Sciences · NIH-11074065

This study is looking at how a hormone called oxytocin might help reduce pain after nerve injuries, and it's for anyone interested in finding new ways to feel better and recover from pain.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11074065 on NIH RePORTER

What this research studies

This research investigates the role of oxytocin in reducing pain following nerve injuries. It aims to understand how oxytocin works in the brain and body, focusing on its effects on pain recovery. By studying the pharmacokinetics of oxytocin in both blood and brain tissues, the researchers will determine the best ways to administer it for maximum benefit. The study will also explore the specific pathways through which oxytocin influences pain perception and recovery.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced nerve injuries and are dealing with acute or chronic pain.

Not a fit: Patients with pain not related to nerve injuries or those who do not respond to oxytocin may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments for managing pain after nerve injuries, improving recovery outcomes for patients.

How similar studies have performed: Previous research has shown promising results with oxytocin in pain management, but this specific approach is novel and aims to refine dosing and administration methods.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.