How oxytocin affects social attention and behavior in adults with autism

Oxytocin Modulation of Neural Circuit Function and Behavior

NIH-funded research New York University School of Medicine · NIH-11379691

Seeing if oxytocin can help social attention and interactions in adults with autism.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNew York University School of Medicine NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11379691 on NIH RePORTER

What this research studies

This project brings together labs that study oxytocin from molecules to brain circuits and behavior, including work with adults who have autism and complementary animal and cellular experiments. Researchers will measure how oxytocin changes brain activity and behavior, compare different delivery methods, and look at how state or experience alters its effects. The team will use brain recordings, imaging, and behavioral tests to explain why past human results have been inconsistent. Findings aim to show who might benefit and how oxytocin-based approaches could be used more precisely and safely.

Who could benefit from this research

Good fit: Adults diagnosed with autism spectrum disorder who experience social attention or interaction difficulties and who can travel to study visits are the most likely candidates for participation.

Not a fit: Children, people without social-communication challenges, or those not eligible for adult-focused protocols are unlikely to benefit directly from this project.

Why it matters

Potential benefit: Could point to better-targeted oxytocin-based approaches to improve social attention and interactions for some autistic adults.

How similar studies have performed: Previous human trials of oxytocin have shown mixed results, so this project builds on inconsistent findings to clarify when and how oxytocin might help.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.