How oxytocin affects pain sensitivity after injury

Oxytocin-mediated modulation of peripheral mechanical sensibility after injury

NIH-funded research Wake Forest University Health Sciences · NIH-11074061

This study is looking at how a hormone called oxytocin might help reduce pain and improve healing after nerve injuries, and it's for anyone dealing with pain from such injuries.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11074061 on NIH RePORTER

What this research studies

This research investigates the role of oxytocin in modulating pain sensitivity following nerve injuries. It aims to understand how oxytocin interacts with specific nerve fibers that transmit pain signals and how this interaction can influence recovery from injury. By studying both injured and uninjured nerve pathways, the research seeks to uncover the mechanisms by which oxytocin may help alleviate pain and promote healing. The findings could lead to new therapeutic strategies for managing pain in patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced nerve injuries and are dealing with acute or chronic pain.

Not a fit: Patients with pain not related to nerve injuries or those who do not respond to oxytocin treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide new insights into pain management and recovery strategies for patients suffering from nerve injuries.

How similar studies have performed: Previous research has shown promising results in using oxytocin for pain modulation, suggesting that this approach could be effective.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.