How our genes change during learning and memory.
The epigenetic encoding of learning and memory
This study is looking at how learning and memory experiences change the way our brain's genes work, which could help us understand more about brain function and conditions that affect it, so it's for anyone interested in how our brains learn and remember things.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11062757 on NIH RePORTER |
What this research studies
This research investigates how the brain's genetic material, specifically chromatin, changes in response to learning and memory experiences. By examining the molecular mechanisms that control gene expression, the study aims to understand how these changes can affect brain function and potentially lead to neurological disorders. The researchers will utilize advanced techniques from the field of epigenetics to explore how environmental cues influence gene transcription in the brain. This work could provide insights into the biological basis of learning and memory, as well as the impact of disruptions in these processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing memory-related disorders or those interested in understanding the biological mechanisms of learning.
Not a fit: Patients with conditions unrelated to memory or learning, such as purely physical ailments, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for neurological and mental health disorders linked to memory and learning dysfunction.
How similar studies have performed: Previous research in epigenetics has shown promise in understanding neurological disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Korb, Erica Megan — University of Pennsylvania
- Study coordinator: Korb, Erica Megan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.