How oral health affects metabolism and inflammation in HIV patients on treatment
The Impact of Oral Health on Metabolism and Persistent Inflammation in HIV Patients on Antiretroviral Therapy (OHART)
This study is looking at how oral health, like cavities and gum disease, affects the overall health of people living with HIV who are on treatment, especially those with other health issues like diabetes or heart disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10814770 on NIH RePORTER |
What this research studies
This research investigates the relationship between oral health and overall health in patients living with HIV who are receiving antiretroviral therapy. It aims to understand how oral diseases, such as cavities and gum disease, impact metabolic issues and inflammation in these patients, particularly those with other chronic conditions. By combining expertise from dental and medical fields, the study seeks to fill knowledge gaps regarding the oral health status of this population. The research will involve assessing the prevalence of oral health problems and their association with metabolic complications like cardiovascular disease and diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients living with HIV who are on antiretroviral therapy and may also have other chronic health conditions.
Not a fit: Patients who are not living with HIV or those who are not on antiretroviral therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved oral health management and overall health outcomes for HIV patients.
How similar studies have performed: Previous research has indicated a significant prevalence of oral health issues in HIV patients, suggesting that this approach is based on established findings.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Omolehinwa, Temitope T — University of Pennsylvania
- Study coordinator: Omolehinwa, Temitope T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.