How opioid use disorder medications affect sleep apnea

The impact of central sleep apnea in patients receiving medications for opioid use disorder

['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10931746

This study is looking at how medications for opioid use disorder might affect sleep apnea in patients, and it wants to see how sleep problems relate to sleep quality, emotional well-being, and cravings for drugs, so we can better understand how these issues might impact recovery.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-10931746 on ClinicalTrials.gov

What this research studies

This research investigates the effects of medications used to treat opioid use disorder on the occurrence of central sleep apnea in patients. It aims to identify patients experiencing sleep apnea while on these medications and compare their sleep quality, emotional health, and drug cravings to those without sleep issues. By using home sleep apnea testing and polysomnography, the study will explore how sleep apnea may influence relapse rates and treatment retention in individuals undergoing medication treatment for opioid use disorder.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are receiving medication treatment for opioid use disorder and may be experiencing sleep apnea.

Not a fit: Patients who are not receiving medication treatment for opioid use disorder or those without any sleep-disordered breathing may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for patients with opioid use disorder by addressing sleep-related issues that may contribute to relapse.

How similar studies have performed: Previous research has indicated that sleep apnea can significantly impact health outcomes in various populations, suggesting that this study's approach may yield valuable insights.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.