How opioid prescriptions affect patients with Alzheimer's and related dementias

Opioid Prescribing Practices and Health Outcomes among Patients with Alzheimer's Disease and Related Dementia

NIH-funded research Ohio State University · NIH-11091654

This study looks at how prescribing opioids affects people with Alzheimer's and related dementias, especially in managing their chronic pain, to see if these medications help or hurt their thinking skills, so we can make better choices for their care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-11091654 on NIH RePORTER

What this research studies

This research investigates the impact of opioid prescribing practices on patients suffering from Alzheimer's disease and related dementias (ADRD). It aims to understand how these medications influence health outcomes, particularly in managing chronic pain, which is prevalent among ADRD patients. The study will utilize longitudinal data to assess whether opioid use improves or worsens cognitive function in this population, addressing a critical gap in current pain management guidelines. By focusing on the unique needs of ADRD patients, the research seeks to inform better treatment decisions for pain relief.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias who are experiencing chronic pain and may be prescribed opioids.

Not a fit: Patients who do not have Alzheimer's disease or related dementias, or those not experiencing chronic pain, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies for patients with Alzheimer's and related dementias, enhancing their overall quality of life.

How similar studies have performed: While there is ongoing research into opioid use in older adults, this specific focus on Alzheimer's and related dementias is relatively novel and addresses a significant gap in the literature.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.