How opioid and stimulant use changes over time and affects overdose risk
The short and long-term dynamics of opioid/stimulant use: Mixed methods to inform overdose prevention and treatment related to polysubstance use
Researchers will follow people who use opioids and stimulants to track their use patterns, treatment experiences, and overdose outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11364697 on NIH RePORTER |
What this research studies
If you take part, researchers will follow people in the community who use both opioids and stimulants over months and years to capture when and how co-use happens. The team will use a mix of surveys, interviews, and health records to collect short-term and long-term information about drug use, treatment visits, and overdoses. They will link these data over time to see how starting or stopping treatment relates to changes in co-use and overdose risk. The goal is to identify moments and patterns where prevention or treatment could help reduce overdoses.
Who could benefit from this research
Good fit: Adults who currently or recently use opioids and stimulants in community settings and who are willing to complete follow-up surveys or interviews and allow access to relevant health or mortality records are the ideal candidates.
Not a fit: People who do not use opioids or stimulants, who only use a single substance without co-use, or who are unwilling to provide follow-up information or records are unlikely to receive direct benefit from participation.
Why it matters
Potential benefit: If successful, this work could guide better prevention and treatment approaches that reduce overdoses among people who use both opioids and stimulants.
How similar studies have performed: Prior work documents rising stimulant-involved overdoses but few proven treatments for stimulant co-use exist, so this project builds on limited evidence and aims to fill important knowledge gaps.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Genberg, Becky Lynn — Johns Hopkins University
- Study coordinator: Genberg, Becky Lynn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.