How olfactory sensory neuron axons interact and organize in the brain
Dynamic interactions among olfactory sensory neuron axons
This study is looking at how the tiny nerve fibers that help us smell grow and connect in the brain, which could help us understand more about how our sense of smell works and lead to better treatments for smell-related issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10685631 on NIH RePORTER |
What this research studies
This research investigates the complex interactions among olfactory sensory neuron axons as they develop and organize in the brain. By examining how these axons fasciculate and converge in the olfactory bulb, the study aims to uncover the molecular mechanisms that guide their growth and targeting. The research utilizes advanced techniques to analyze the axoskeleton and organelles of these neurons, providing insights into the fundamental processes of neural wiring. Patients may benefit from a better understanding of olfactory function and potential treatments for related disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are adults aged 21 and older who experience olfactory dysfunction or related neurological issues.
Not a fit: Patients with conditions unrelated to olfactory function or those under 21 years old may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for conditions affecting the sense of smell and related neurological disorders.
How similar studies have performed: While the specific interactions among olfactory sensory neuron axons are less explored, similar research in neural wiring has shown promising results in understanding sensory systems.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Greer, Charles a — Yale University
- Study coordinator: Greer, Charles a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.