How obesity and diabetes-related metabolism may raise cancer risk
Metabolic Dysregulation and Cancer Risk Program: Coordinating Center
Researchers are developing shared ways to measure how obesity-related metabolic problems, like those in type 2 diabetes, may increase cancer risk to help people at risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | George Washington University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-11164589 on NIH RePORTER |
What this research studies
This project brings together experts in nutrition, exercise, metabolism, body composition, biostatistics, and bioinformatics to understand links between obesity-related metabolic problems and cancer. Teams will create common measurements across different cancer types, analyze patient data and biological samples, and use computational methods to identify molecular pathways that connect metabolic dysregulation to cancer initiation and development. The coordinating center at George Washington University will manage collaboration, standardize protocols, harmonize data, and support statistical and computational analyses across sites. The work focuses on finding measurable targets that could be used in future prevention strategies or trials.
Who could benefit from this research
Good fit: People with obesity, metabolic syndrome, or type 2 diabetes, and those with a history of obesity-linked cancers are the most likely candidates for related studies and sample donations.
Not a fit: People without obesity-related metabolic problems or those seeking immediate cancer treatment, rather than prevention or risk research, are unlikely to benefit directly from this work.
Why it matters
Potential benefit: Could identify measurable metabolic targets and risk markers that help prevent cancer in people with obesity or type 2 diabetes.
How similar studies have performed: Previous research has linked obesity and diabetes to higher cancer risk, but this coordinated effort to standardize measures and discover metabolic prevention targets is a newer, larger-scale approach.
Where this research is happening
Washington, United States
- George Washington University — Washington, United States (Active)
Researchers
- Principal investigator: Temprosa, Marinella — George Washington University
- Study coordinator: Temprosa, Marinella
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.