How obesity affects the immune response to gut viruses
Immunometabolic regulation of enteric viral infection
['FUNDING_FELLOWSHIP'] · WASHINGTON UNIVERSITY · NIH-10901522
This study is looking at how being overweight affects the body's ability to fight off stomach viruses like norovirus, and it's for anyone interested in understanding how diet and weight can influence our immune system.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10901522 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of diet-induced obesity on the immune response to gastrointestinal viruses, particularly norovirus. It aims to understand how obesity-related inflammation alters the body's ability to fight off these infections. By studying the immune responses in both animal models and human patients, the research seeks to uncover the mechanisms that may lead to increased susceptibility to viral infections in obese individuals. The findings could provide insights into how dietary factors influence viral immunity.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing obesity and related gastrointestinal symptoms.
Not a fit: Patients who are not obese or do not have gastrointestinal symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating viral infections in obese patients.
How similar studies have performed: Previous research has shown that obesity can significantly impact immune responses, suggesting that this study's approach may yield valuable insights.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WRIGHT, JASMINE — WASHINGTON UNIVERSITY
- Study coordinator: WRIGHT, JASMINE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus