How obesity affects the effectiveness of radiotherapy in cancer treatment
The Impact of Obesity on Radiotherapy Anti-Tumor Effects
This study is looking into how being overweight might affect the success of radiation therapy for cancer, with the goal of finding ways to help overweight patients get better results from their treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11044199 on NIH RePORTER |
What this research studies
This research investigates the relationship between obesity and the effectiveness of radiotherapy in treating cancer. It aims to understand why obese cancer patients often experience reduced benefits from radiotherapy and higher rates of cancer recurrence. The study will explore the biological mechanisms behind this resistance, focusing on how obesity-related hormones and immune responses may alter the effectiveness of cancer therapies. By examining these factors, the research seeks to identify potential strategies to improve treatment outcomes for obese cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are obese individuals diagnosed with cancer who are undergoing or considering radiotherapy.
Not a fit: Patients who are not obese or those without a cancer diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved radiotherapy strategies for obese cancer patients, enhancing their treatment outcomes.
How similar studies have performed: Previous studies have indicated that obesity can negatively impact cancer treatment outcomes, suggesting that this research addresses a significant and relevant issue.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Monjazeb, Arta Monir — University of California at Davis
- Study coordinator: Monjazeb, Arta Monir
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.