How obesity affects HIV and its treatment

Effect of obesity on HIV pathogenesis, antiretroviral therapy, and metabolic comorbidities

NIH-funded research Oregon Health & Science University · NIH-10852482

This study looks at how being overweight affects people with HIV, especially how it might change how well their treatment works and lead to other health problems, with the goal of finding better ways to help those who are living with both HIV and obesity.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University NIH-funded
Lab location1 site (Portland, United States)
Project IDNIH-10852482 on NIH RePORTER

What this research studies

This research investigates the impact of obesity on individuals living with HIV, particularly focusing on how it influences the effectiveness of antiretroviral therapy (ART) and the development of related health issues. The study aims to understand the mechanisms by which obesity and metabolic diseases interact with HIV, potentially leading to chronic inflammation and other complications. By examining these relationships, the research seeks to identify ways to improve health outcomes for HIV patients who are also dealing with obesity and metabolic disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who also have obesity or metabolic conditions such as prediabetes.

Not a fit: Patients who are not living with HIV or do not have obesity or related metabolic conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for HIV patients who are obese, enhancing their overall health and quality of life.

How similar studies have performed: Previous research has shown that obesity can significantly impact the health of individuals with HIV, suggesting that this area of study is both relevant and necessary.

Where this research is happening

Portland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immuno-Deficiency SyndromeAcquired Immunologic Deficiency SyndromeAcquired Immunodeficiency Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.