How obesity affects HIV and its treatment
Effect of obesity on HIV pathogenesis, antiretroviral therapy, and metabolic comorbidities
This study looks at how being overweight affects people with HIV, especially how it might change how well their treatment works and lead to other health problems, with the goal of finding ways to help them feel better and stay healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10657424 on NIH RePORTER |
What this research studies
This research investigates the impact of obesity on individuals living with HIV, particularly focusing on how excess weight influences the effectiveness of antiretroviral therapy (ART) and contributes to metabolic diseases. The study aims to understand the mechanisms behind these interactions, including how obesity may exacerbate inflammation and other health issues in HIV patients. By examining the relationship between body composition and HIV pathogenesis, the research seeks to identify potential strategies for improving health outcomes in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living with HIV who are also experiencing obesity or metabolic disorders.
Not a fit: Patients who are not living with HIV or those who do not have obesity or related metabolic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment strategies for HIV patients who are also dealing with obesity, ultimately improving their overall health and quality of life.
How similar studies have performed: Other research has indicated that obesity can significantly impact the health of individuals with HIV, suggesting that this area of investigation is both relevant and necessary.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Roberts, Charles T — Oregon Health & Science University
- Study coordinator: Roberts, Charles T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.