How obesity affects COVID-19 infection and its impact on metabolic diseases.

Impact of obesity on SARS-CoV-2 infection and reciprocal effects of SARS-CoV-2 on metabolic disease

['FUNDING_R01'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-10868708

This study is looking at how being overweight might affect how seriously someone gets sick from COVID-19 and how COVID-19 could impact conditions like diabetes and heart disease, so if you're interested in how these health issues connect, you might be able to help us learn more!

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorOREGON HEALTH & SCIENCE UNIVERSITY (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-10868708 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between obesity and the severity of COVID-19 infections, as well as how COVID-19 may influence metabolic diseases like diabetes and cardiovascular conditions. The study will explore whether obesity is an independent risk factor for severe COVID-19 outcomes, even in the absence of other diagnosed conditions. By examining the effects of obesity on the immune response and metabolic processes, the research aims to uncover the reciprocal effects of COVID-19 on metabolic health. Patients may be involved in assessments that help understand these interactions and their implications for treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are living with obesity.

Not a fit: Patients without obesity or those who do not have any metabolic diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of COVID-19 in patients with obesity, potentially reducing severe outcomes.

How similar studies have performed: Previous research has indicated a link between obesity and respiratory diseases, suggesting that this area of investigation could yield valuable insights.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acute Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.