How obesity affects COVID-19 infection and its impact on metabolic diseases.

Who could benefit from this research

What this research studies

This research investigates the relationship between obesity and the severity of COVID-19 infections, as well as how COVID-19 may influence metabolic diseases like diabetes and cardiovascular conditions. The study will explore whether obesity is an independent risk factor for severe COVID-19 outcomes, even in the absence of other diagnosed conditions. By examining the effects of obesity on the immune response and metabolic processes, the research aims to uncover the reciprocal effects of COVID-19 on metabolic health. Patients may be involved in assessments that help understand these interactions and their implications for treatment.

Why it matters

Where this research is happening

• Oregon Health & Science University
  Portland, United States Active

Researchers

• Principal investigator: Roberts, Charles T — Oregon Health & Science University
• Study coordinator: Roberts, Charles T

Related research

Other NIH-funded projects on the same topics.

• Understanding how obesity affects COVID-19 and how COVID-19 impacts metabolism

  This project explores how having obesity changes the way your body responds to COVID-19, and how the virus itself might affect your metabolism.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11117098

• How COVID-19 infection and genes may influence memory and dementia risk

  This study looks at how getting COVID-19 and a person’s genes together affect the chance of developing memory problems and Alzheimer’s disease later in life.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11617103

• Alzheimer’s-related dementia after COVID-19: how SARS-CoV-2 affects the brain and potential drug repurposing

  This research looks at how COVID-19 may contribute to dementia by studying brain inflammation, blood vessel injury, and virus-host interactions, with the goal of finding existing drugs that could help.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11457086

• IL-22’s role in SARS-CoV-2 infection and tissue protection

  A short study to understand how the cytokine IL-22 might help protect tissues during and after COVID-19 infection, especially in people with complications related to acute graft-versus-host disease.

  NIH research University of Oklahoma Hlth Sciences Ctr · Oklahoma City, United States · NIH-11451891

• Maternal SARS-CoV-2 infection and its effects on placenta and child development

  This grant studies how COVID-19 infection during pregnancy might change the placenta and influence a child’s brain development, especially in kids who may be at higher genetic risk for ADHD/ASD.

  NIH research Lieber Institute, INC. · Baltimore, United States · NIH-11402254

• How COVID-19 and genetics influence memory and dementia risk in older adults

  This project studies how getting COVID-19 interacts with people’s genetic makeup to affect the likelihood of cognitive decline and Alzheimer’s disease in older adults from diverse backgrounds.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11401787

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.