How nutrients affect the growth of brain cells and their connections
Nutrient-dependent regulation of neural stem cell proliferation and neural circuit formation
['FUNDING_OTHER'] · UNIVERSITY OF VIRGINIA · NIH-11112187
This study looks at how the food we eat affects the growth of brain cells in fruit flies, helping us learn more about how diet can influence brain health and development.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF VIRGINIA (nih funded) |
| Locations | 1 site (CHARLOTTESVILLE, UNITED STATES) |
| Trial ID | NIH-11112187 on ClinicalTrials.gov |
What this research studies
This research investigates how dietary nutrients influence the growth and development of neural stem cells, which are crucial for forming the diverse types of neurons in the brain. Using the fruit fly as a model organism, the study examines the genetic pathways and molecular mechanisms that control when these stem cells divide and produce neurons. By understanding these processes, the research aims to uncover how external factors like diet can impact brain health and function over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who may be experiencing neurodegenerative disorders such as Alzheimer's disease or autism spectrum disorders.
Not a fit: Patients with acute neurological injuries or those not affected by neurodegenerative conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary recommendations or interventions that promote healthy brain development and function, potentially benefiting individuals with neurodegenerative conditions.
How similar studies have performed: Previous research has shown promising results in understanding the role of diet on neural development, suggesting that this approach could yield valuable insights.
Where this research is happening
CHARLOTTESVILLE, UNITED STATES
- UNIVERSITY OF VIRGINIA — CHARLOTTESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SIEGRIST, SARAH ELIZABETH — UNIVERSITY OF VIRGINIA
- Study coordinator: SIEGRIST, SARAH ELIZABETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease