NIH-funded research R21 grant

How nutrient changes affect daily biological rhythms

Official title: Nutrient-sensitive protein modifications regulate daily biological rhythms

Funded at University of California at Davis · NIH-10826071 · Data updated 2026-11-12

This study looks at how the foods we eat can affect our body's daily rhythms, which are important for staying healthy, and it aims to help people understand how their diet might influence their overall well-being.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis
NIH-funded
Lab location1 site (Davis, United States)
Project startSeptember 15, 2024
Project endAugust 31, 2026
Funding year2024
Award (this year)$241,500
NIH project number1R21AG082480-01A1
Project IDNIH-10826071 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing chronic diseases or conditions related to circadian rhythm disruptions.

Less likely to help

Patients with stable circadian rhythms and no chronic health issues may not receive direct benefits from this research.

What this research studies

This research investigates how nutrient-sensitive protein modifications influence daily biological rhythms, which are crucial for maintaining health. By examining the interactions between circadian clocks in the brain and peripheral organs, the study aims to uncover how metabolic signals from food intake regulate these rhythms. The approach includes analyzing post-translational modifications of proteins that play a role in synchronizing biological processes with the day-night cycle. Patients may benefit from insights into how their dietary habits can impact their overall health and well-being.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for managing chronic diseases linked to circadian rhythm disruptions.

How similar studies have gone: Previous research has shown promising results in understanding the role of circadian rhythms in health, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of California at Davis
    Davis, United States
    Active

Researchers

  • Principal investigator: Chiu, Joanna Chungyen — University of California at Davis
  • Study coordinator: Chiu, Joanna Chungyen

Related research

Other NIH-funded projects on the same topics.

  • UC Davis IGA Innovation Center

    A research center at UC Davis will study gene-edited livestock to improve animal health, safety, and policy through sharing genetic data and findings about genome edits in cattle, pigs, sheep, and goats.

    NIH research University of California at Davis · Davis, United States · NIH-11641870

  • Administrative Core of an equitable breast cancer screening program

    A national program headed from UC Davis is coordinating several research efforts to improve how breast cancer screening is done in community settings.

    NIH research University of California at Davis · Davis, United States · NIH-11622111

  • The role of novelty and surprise in learning for people with Alzheimer’s disease

    A study explores how surprising events affect memory and learning in people related to Alzheimer’s disease, using everyday tasks to see how the brain remembers new information.

    NIH research University of California at Davis · Davis, United States · NIH-11617755

  • Understanding how distraction affects students and how to measure it better

    This grant studies why distracted students, including those with ADHD, struggle in real-life learning and tests a clearer way to measure distraction in everyday settings.

    NIH research University of California at Davis · Davis, United States · NIH-11617018

  • California Partnership for Personalized Nutrition

    A California clinical center is testing personalized dietary approaches to improve blood sugar and health for adults with diabetes by using big data and AI to tailor meals.

    NIH research University of California at Davis · Davis, United States · NIH-11605720

  • Advancing gastric cancer care for Latinos through patient-derived tumor models

    Aimed at Latinos with gastric cancer, this project uses patient-derived tumor models to study how cancer biology and treatments work in real tumors.

    NIH research University of California at Davis · Davis, United States · NIH-11603175

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.