How not having steady access to food may affect memory and dementia risk

The Longitudinal and Dynamic Effects of Food Insecurity on Cognitive Impairment and Dementia Risk

NIH-funded research Harvard University D/b/a Harvard School of Public Health · NIH-11091551

This project looks at whether not having steady access to enough food leads to worse thinking skills and higher dementia risk in adults, especially older people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard University D/b/a Harvard School of Public Health NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11091551 on NIH RePORTER

What this research studies

You would have your food access, diet, medical conditions, mood, and thinking skills tracked over time so researchers can see how changes in food security relate to memory and dementia risk. The team will analyze long-term data to link episodes of food insecurity with later changes in cognitive test scores and dementia diagnoses. They will examine whether poor diet, cardiometabolic problems (like diabetes or high blood pressure), and psychological distress explain any increased risk. Findings are intended to point to possible nutrition or food-support programs to help protect thinking as people age.

Who could benefit from this research

Good fit: Ideal candidates are adults—especially older adults—who have experienced food insecurity or limited access to healthy food.

Not a fit: People who do not face food access problems or whose dementia is driven mainly by non-modifiable genetic causes may not see direct benefit from findings focused on food insecurity.

Why it matters

Potential benefit: If successful, this work could identify food insecurity as a reversible risk factor for cognitive decline and suggest food- and nutrition-focused approaches to lower dementia risk.

How similar studies have performed: Some small cross-sectional studies have linked food insecurity to lower cognitive scores, but rigorous long-term evidence is limited and this longitudinal approach is relatively new.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.