How night shift work affects blood fats and insulin sensitivity

Impact of circulating and tissue-specific lipids on vascular function and insulin sensitivity in chronic night shift workers

NIH-funded research Colorado State University · NIH-11026417

This study is looking at how working night shifts might mess with your body's natural clock and affect your heart health and blood sugar, especially for people who do this kind of work, to find ways to help them stay healthier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColorado State University NIH-funded
Lab location1 site (Fort Collins, United States)
Project IDNIH-11026417 on NIH RePORTER

What this research studies

This research investigates the health impacts of working night shifts, particularly how it disrupts normal biological rhythms and affects blood fats and insulin sensitivity. The study focuses on understanding the relationship between circadian misalignment and increased risks of cardiovascular disease and Type 2 diabetes among shift workers. By analyzing blood samples and tissue-specific lipids, researchers aim to uncover the mechanisms behind these health risks and explore potential strategies for improving health outcomes in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who work night shifts and experience circadian misalignment.

Not a fit: Patients who do not work night shifts or have no issues with sleep patterns may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to targeted interventions that improve cardiovascular health and insulin sensitivity in night shift workers.

How similar studies have performed: Previous research has indicated that circadian misalignment can negatively impact health, suggesting that this study builds on established findings rather than exploring a completely novel approach.

Where this research is happening

Fort Collins, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.