How neighborhood and socioeconomic conditions affect heart health and lifespan

Area-level Socio-economic Conditions and Individual-level Health and Mortality: Exploring Place-Based Mechanisms and Individual-level Psychosocial Processes

NIH-funded research Utah State Higher Education System--University of Utah · NIH-11251332

This work looks at how where adults live and personal stressors relate to heart disease risk and early death among U.S. adults ages 25–74.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUtah State Higher Education System--University of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11251332 on NIH RePORTER

What this research studies

Researchers will combine long-term survey data from the MIDUS study with linked state vital and administrative records from the Utah Population Database to study adults' health and mortality over time. They will link geocoded residential addresses to area-level measures like neighborhood poverty, employment, and resources while also using individual measures such as mental stress, alcohol use, and demographic factors. Analyses will test whether individual psychosocial processes explain or change how place affects cardiovascular disease and premature death across different regions and population groups. The goal is to identify place-based mechanisms that raise risk so policies or prevention programs can better target high-risk areas.

Who could benefit from this research

Good fit: Adults aged 25–74, especially U.S. residents from diverse neighborhoods, including Black participants represented in the MIDUS oversample and Utah residents included in the UPDB.

Not a fit: Children, people outside the 25–74 age range, and individuals without stable residential records are unlikely to be represented and may not directly benefit.

Why it matters

Potential benefit: If successful, this work could pinpoint neighborhood and personal factors that increase heart disease and early death, guiding community-level policies and prevention efforts to protect adults in high-risk areas.

How similar studies have performed: Prior studies have linked neighborhood socioeconomic conditions to heart disease and mortality, and this project uses larger, linked longitudinal datasets to better clarify the underlying reasons.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseases
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.