How neighborhood and social factors influence when people get knee replacement

Social Determinants and Timeliness of Total Knee Replacement A National Perspective

NIH-funded research University of Alabama at Birmingham · NIH-11252622

This project looks at how neighborhood, healthcare access, and social circumstances affect when adults who need knee replacement actually receive surgery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11252622 on NIH RePORTER

What this research studies

If you have knee arthritis, this project uses a national knee-replacement registry plus X-ray readings, maps of where people live, and Medicare records to understand timing of surgery. Researchers will classify whether operations happened earlier than ideal or at the right time based on symptoms and function. They will then examine how local healthcare access and the built environment (for example, transportation, clinics, sidewalks) relate to who gets surgery sooner or later and how much people improve afterward. The findings aim to identify social and neighborhood barriers that delay or hasten knee replacement so clinicians and policymakers can target help.

Who could benefit from this research

Good fit: Adults with moderate-to-severe knee osteoarthritis who are candidates for or have received total knee replacement, especially Medicare beneficiaries and patients in the FORCE-TJR registry.

Not a fit: People without knee osteoarthritis, those not considering surgery, or patients outside participating hospitals or the registry are unlikely to be directly impacted by participation in this project.

Why it matters

Potential benefit: If successful, the work could help direct knee replacement to people who will benefit most and reduce delays and inequities in access.

How similar studies have performed: Previous research has linked social factors to access and use of joint replacement, but a national analysis combining radiographs, neighborhood data, and Medicare records to study timing of surgery is largely new.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.