NIH-funded research R01 grant

How motivation affects movement in the brain

Official title: Neural Mechanisms of Motivated Movement

Funded at Carnegie-Mellon University · NIH-11045764 · Data updated 2026-11-12

This study is looking at how motivation affects our ability to move and perform tasks, like in sports, by exploring the role of a brain chemical called dopamine, which could help us find better ways to improve movement skills for people who struggle with motivation or movement issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCarnegie-Mellon University
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startApril 15, 2023
Project endFebruary 29, 2028
Funding year2025
Award (this year)$319,159
NIH project number5R01NS129098-03
Project IDNIH-11045764 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with movement disorders or those experiencing motivational issues affecting their physical performance.

Less likely to help

Patients who do not have any movement-related conditions or motivational challenges may not benefit from this research.

What this research studies

This research investigates the neural mechanisms that influence how motivation impacts movement performance. By examining the role of dopamine in the brain, the study aims to understand how varying levels of motivation can enhance or hinder motor skills, such as in high-pressure situations like sports. The researchers will conduct experiments to analyze how dopamine interacts with neurons in the motor cortex, potentially leading to insights on improving movement control. This work could have implications for treating conditions related to movement and motivation.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for enhancing motor performance in individuals with movement disorders or those facing motivational challenges.

How similar studies have gone: Previous research has shown promising results in understanding the role of dopamine in motor control, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Carnegie-Mellon University
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Chase, Steven M — Carnegie-Mellon University
  • Study coordinator: Chase, Steven M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.