How mosquitoes and malaria parasites become resistant to insecticides and medicines
Understanding the Dynamics of Insecticide and Drug Resistance through Integrated Studies of Vectors, Parasites and Interventions
This project follows mosquitoes and malaria parasites across different sites to find out why bed nets, sprays, and antimalarial drugs stop working for people at risk of malaria.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11404830 on NIH RePORTER |
What this research studies
If you live in a malaria-prone area, researchers will collect mosquito and parasite samples from communities and clinics where malaria control tools have been used. They will compare places with different intervention histories (for example, long-lasting insecticidal nets, indoor spraying, and drug use) and track changes in resistance over time. The team will link resistance patterns in mosquitoes and parasites to local transmission levels and treatment outcomes. Findings will be used to guide which control tools work best in each setting.
Who could benefit from this research
Good fit: People living in malaria-endemic sentinel sites—especially children, pregnant women, and patients who seek care at participating clinics—are the most likely candidates to take part or provide samples.
Not a fit: People who live outside the participating malaria-endemic sites or who do not receive care at the partner clinics are unlikely to benefit directly from participating.
Why it matters
Potential benefit: This work could help keep bed nets, spraying, and malaria medicines effective by guiding better choices of interventions for specific communities.
How similar studies have performed: Surveillance programs like this have previously helped shape malaria control policies, but combining detailed vector and parasite resistance tracking across multiple, diverse sites is a newer, more integrated approach.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Cui, Liwang — University of South Florida
- Study coordinator: Cui, Liwang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.