How mosquito behavior and physiology are influenced by biogenic amines in malaria.
Official title: Biogenic amines, malaria and manipulation of mosquito physiology and behavior.
Funded at University of Idaho · NIH-10875403 · Data updated 2026-11-12
This study looks at how certain chemicals in the blood of people with malaria affect how mosquitoes behave and live, which could help us find new ways to stop the spread of malaria.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Idaho NIH-funded |
| Lab location | 1 site (Moscow, United States) |
| Project start | August 8, 2022 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $541,212 |
| NIH project number | 5R01AI165481-03 |
| Project ID | NIH-10875403 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living in malaria-endemic regions who may be affected by malaria transmission.
✕Less likely to help
Patients who do not live in malaria-endemic areas or who are not at risk of malaria infection may not benefit from this research.
What this research studies
This research investigates how biogenic amines like histamine and serotonin affect mosquito behavior and physiology, particularly in the context of malaria transmission. By examining how these substances, which are present in the blood of malaria-infected individuals, influence mosquito feeding behavior, reproduction, and lifespan, the study aims to uncover new insights into malaria transmission dynamics. The research employs a combination of laboratory experiments and modeling to assess the impact of these amines on mosquito infection success and behavior. This could lead to innovative strategies for controlling malaria spread by targeting mosquito biology.
Why it matters
Potential benefit: If successful, this research could lead to new methods for reducing malaria transmission by manipulating mosquito behavior.
How similar studies have gone: While the specific approach of manipulating mosquito behavior through biogenic amines is innovative, similar research has shown promise in understanding mosquito biology and its implications for disease transmission.
Where this research is happening
-
University of Idaho
Moscow, United States Active
Researchers
- Principal investigator: Luckhart, Shirley — University of Idaho
- Study coordinator: Luckhart, Shirley
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.