How mixed metal exposures affect children's brain health in rural Bangladesh

Building Capacity to study mixed metal-induced neurotoxicity in rural Bangladeshi children-A1

NIH-funded research Sam Houston State University · NIH-11398350

This project helps Bangladeshi scientists learn better ways to measure how mixtures of metals like arsenic, lead, manganese, and cadmium may harm children's brain development.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSam Houston State University NIH-funded
Lab location1 site (Huntsville, United States)
Project IDNIH-11398350 on NIH RePORTER

What this research studies

Local clinicians and researchers in rural Bangladesh will be trained in collecting exposure data, taking biological samples, and doing child development and neurobehavioral tests. Teams will measure levels of multiple metals and link those exposures to learning, behavior, and developmental findings in infants and school-age children. U.S. universities will provide hands-on training, lab methods, and data-analysis support while Bangladeshi partners lead field work. The goal is to build local capacity so future studies and public-health actions can better protect children's brain health.

Who could benefit from this research

Good fit: Children living in rural areas of Bangladesh with potential exposure to arsenic, lead, manganese, or cadmium—including infants, toddlers, and school-age children—are the intended focus.

Not a fit: People without metal exposure concerns, those living outside the affected rural areas, or adults not enrolled in the project are unlikely to see direct benefits from this grant.

Why it matters

Potential benefit: If successful, this work could lead to earlier detection of metal-related developmental problems and stronger local programs to prevent or reduce children's exposure.

How similar studies have performed: Previous studies in Bangladesh and elsewhere have linked single-metal exposures to developmental harms, but combining mixed-metal exposure analysis with local capacity building is less common and relatively new.

Where this research is happening

Huntsville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.