How mitochondria influence cell development and function
The role of mitochondrial regulation in cell lineage specification and function
['FUNDING_OTHER'] · OKLAHOMA MEDICAL RESEARCH FOUNDATION · NIH-11118286
This study is looking at how tiny powerhouses in our cells, called mitochondria, help decide how cells grow and work, which is important for healthy development, and it could lead to new treatments for issues like developmental problems and cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OKLAHOMA MEDICAL RESEARCH FOUNDATION (nih funded) |
| Locations | 1 site (OKLAHOMA CITY, UNITED STATES) |
| Trial ID | NIH-11118286 on ClinicalTrials.gov |
What this research studies
This research investigates the role of mitochondria in determining how cells develop and function. It focuses on understanding how changes in mitochondrial activity can affect cell lineage specification, which is crucial for proper cell development. By using advanced imaging techniques, the research aims to uncover the mechanisms by which mitochondria regulate cellular processes and respond to signals that guide cell fate. The findings could lead to new therapeutic strategies for conditions where these processes go awry, such as developmental defects and cancers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with developmental defects or cancers linked to mitochondrial dysfunction.
Not a fit: Patients with conditions unrelated to mitochondrial function or cell lineage specification may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for developmental disorders and cancers by targeting mitochondrial functions.
How similar studies have performed: Previous research has shown promising results in understanding mitochondrial roles in cell function, suggesting that this approach could yield valuable insights.
Where this research is happening
OKLAHOMA CITY, UNITED STATES
- OKLAHOMA MEDICAL RESEARCH FOUNDATION — OKLAHOMA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHAO, MENG — OKLAHOMA MEDICAL RESEARCH FOUNDATION
- Study coordinator: ZHAO, MENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers