How mitochondria influence cell development and function
The role of mitochondrial regulation in cell lineage specification and function
This study is looking at how tiny parts of our cells called mitochondria help decide how cells grow and work, which is important for healthy development, and it hopes to find ways to fix problems that can lead to diseases like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project ID | NIH-10851988 on NIH RePORTER |
What this research studies
This research investigates the role of mitochondria in determining how cells develop and function. It focuses on how changes in mitochondrial activity can affect cell lineage specification, which is crucial for proper cell development. By using advanced imaging techniques, the research aims to uncover the mechanisms by which mitochondria regulate cellular processes and how these processes can go awry, leading to developmental defects or cancers. The findings could provide insights into potential therapies for conditions caused by mitochondrial dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with developmental disorders or cancers that may be related to mitochondrial dysfunction.
Not a fit: Patients with conditions unrelated to mitochondrial function or those who do not have developmental disorders or cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating developmental disorders and cancers linked to mitochondrial dysfunction.
How similar studies have performed: Previous research has shown promising results in understanding mitochondrial roles in cellular processes, suggesting that this approach could yield valuable insights.
Where this research is happening
Oklahoma City, United States
- Oklahoma Medical Research Foundation — Oklahoma City, United States (Active)
Researchers
- Principal investigator: Zhao, Meng — Oklahoma Medical Research Foundation
- Study coordinator: Zhao, Meng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.