How Mitochondria Guide Cell Development and Function
The role of mitochondrial regulation in cell lineage specification and function
['FUNDING_OTHER'] · OKLAHOMA MEDICAL RESEARCH FOUNDATION · NIH-11123093
This work explores how tiny powerhouses inside our cells, called mitochondria, help cells develop correctly and function properly, especially in understanding how problems in this process can lead to cancers.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OKLAHOMA MEDICAL RESEARCH FOUNDATION (nih funded) |
| Locations | 1 site (OKLAHOMA CITY, UNITED STATES) |
| Trial ID | NIH-11123093 on ClinicalTrials.gov |
What this research studies
Our bodies are made of many different types of cells, each with a special job, and this project looks at how cells decide what they will become. Mitochondria, often called the 'power plants' of our cells, play a crucial role in this process by providing energy and signals. When something goes wrong with how mitochondria guide cell development, it can lead to serious health issues, including various types of cancer. This research aims to uncover the detailed ways mitochondria influence cell fate and daily functions, building on previous findings that highlight their importance.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation but aims to benefit individuals affected by cancers and other diseases linked to cell development issues in the future.
Not a fit: Patients seeking immediate treatment or direct clinical intervention would not receive benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to new ways to correct cellular problems and potentially develop new treatments for cancers and other developmental defects by targeting mitochondrial function.
How similar studies have performed: Preliminary and published work from this research group has already shown important roles for mitochondrial metabolism and dynamics in cell development, suggesting a strong foundation for this project.
Where this research is happening
OKLAHOMA CITY, UNITED STATES
- OKLAHOMA MEDICAL RESEARCH FOUNDATION — OKLAHOMA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHAO, MENG — OKLAHOMA MEDICAL RESEARCH FOUNDATION
- Study coordinator: ZHAO, MENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers