How mitochondria affect the development of mammary glands
Mitophagy Dependent Regulation of Mammary Gland Differentiation
['FUNDING_R01'] · TEXAS A&M AGRILIFE RESEARCH · NIH-10903915
This study is looking at how tiny parts of our cells called mitochondria help breast tissue grow and stay healthy, especially by recycling damaged ones, which could help us understand more about normal breast development and conditions like breast cancer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEXAS A&M AGRILIFE RESEARCH (nih funded) |
| Locations | 1 site (College Station, UNITED STATES) |
| Trial ID | NIH-10903915 on ClinicalTrials.gov |
What this research studies
This research investigates the role of mitochondria in the differentiation of mammary gland tissue. It focuses on a process called mitophagy, which recycles damaged mitochondria to maintain cellular health and respond to stress. By understanding how mitophagy operates during mammary gland development, the research aims to uncover the signaling pathways that regulate this process. This could provide insights into how mitochondrial function impacts both normal development and diseases like breast cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a family history of breast cancer or those at high risk for developing breast cancer.
Not a fit: Patients who are not at risk for breast cancer or have no history of related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating breast cancer by targeting mitochondrial health.
How similar studies have performed: Other research has shown promising results in understanding mitochondrial roles in various diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
College Station, UNITED STATES
- TEXAS A&M AGRILIFE RESEARCH — College Station, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PORTER, WESTON W — TEXAS A&M AGRILIFE RESEARCH
- Study coordinator: PORTER, WESTON W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Breast Cancer, Cancers