How mitochondria affect stress responses in humans
Mitochondrial regulation of stress reactivity in humans
['FUNDING_R01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10824357
This study is looking at how the health of tiny energy factories in our cells, called mitochondria, affects how our bodies handle stress, especially for people dealing with anxiety or heart issues, and it involves some stress tests to see how different people react.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10824357 on ClinicalTrials.gov |
What this research studies
This research investigates how mitochondrial function influences the body's response to stress, particularly in relation to conditions like anxiety and cardiovascular health. By examining the physiological systems involved in stress reactivity, such as the autonomic nervous system and the hypothalamic-pituitary-adrenal axis, the study aims to uncover the biological mechanisms that lead to differences in stress responses among individuals. Participants may undergo standardized stress tests to measure their physiological reactions, providing insights into how mitochondrial health impacts overall stress regulation.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing high levels of stress or anxiety, as well as those with conditions related to stress dysregulation.
Not a fit: Patients with stable, low-stress lifestyles or those not experiencing any stress-related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of stress-related health issues, potentially reducing the risk of future diseases.
How similar studies have performed: Previous research has shown promising results in understanding the role of mitochondrial function in stress responses, suggesting that this approach could yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PICARD, MARTIN — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: PICARD, MARTIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.