How migrating cells influence tissue development
Official title: Nonautonomous control of substrate morphogenesis by migrating cells
Funded at California State Univ, Monterey Bay · NIH-11039700 · Data updated 2026-11-12
This study looks at how moving cells in fruit flies work with their surroundings to help build and shape tissues, using special imaging tools to see these interactions as they happen.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California State Univ, Monterey Bay NIH-funded |
| Lab location | 1 site (Seaside, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $142,996 |
| NIH project number | 1R03HD117199-01 |
| Project ID | NIH-11039700 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to tissue development or repair, such as certain cancers or developmental disorders.
✕Less likely to help
Patients with conditions unrelated to tissue development or those who are not undergoing any tissue repair processes may not benefit from this research.
What this research studies
This research investigates how migrating cells interact with their surrounding environment to influence tissue formation and development. By studying the collective migration of specific cells in fruit flies, the researchers aim to understand how these cells affect the growth and behavior of the tissues they move along. The study employs advanced imaging techniques to observe these interactions in real-time, providing insights into the cellular mechanisms involved in tissue assembly.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving tissue regeneration and repair in various medical conditions.
How similar studies have gone: Previous research has shown promising results in understanding cell migration and its effects on tissue development, suggesting that this approach could yield valuable insights.
Where this research is happening
-
California State Univ, Monterey Bay
Seaside, United States Active
Researchers
- Principal investigator: Macabenta, Frank D — California State Univ, Monterey Bay
- Study coordinator: Macabenta, Frank D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.