How microbes evolve and interact in structured environments
Evolutionary dynamics of dense, spatially structured, and antagonistic microbial populations
['FUNDING_OTHER'] · CORNELL UNIVERSITY · NIH-10870149
This study looks at how tiny germs in our gut grow and work together in different environments, which could help us find better ways to support good germs and keep harmful ones in check for better health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORNELL UNIVERSITY (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-10870149 on ClinicalTrials.gov |
What this research studies
This research investigates how microbial populations, such as those found in the human gut, evolve and interact within structured environments. By examining the spatial arrangements of these microbes and their antagonistic relationships, the study aims to understand how these factors influence their evolutionary dynamics. The researchers utilize experimental evolution, synthetic biology, and mathematical modeling to explore these interactions, which could lead to insights into how to better manage microbial communities in health and disease. The findings may help in developing strategies to enhance beneficial microbial interactions and suppress harmful ones.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions influenced by microbial populations, such as gastrointestinal disorders or skin infections.
Not a fit: Patients with conditions unrelated to microbial interactions or those not affected by microbiome dynamics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing human microbiomes, potentially enhancing health and preventing infections.
How similar studies have performed: Previous research has shown that understanding microbial interactions in structured environments can lead to significant advancements in microbiome management, indicating a promising avenue for this study.
Where this research is happening
ITHACA, UNITED STATES
- CORNELL UNIVERSITY — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GIOMETTO, ANDREA — CORNELL UNIVERSITY
- Study coordinator: GIOMETTO, ANDREA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.