How methionine affects cell growth and survival
Metabolic signals regulating cell growth versus survival
This study is looking at how a special nutrient called methionine affects how our cells grow and stay healthy, which could help us understand more about aging and diseases that come with getting older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10763807 on NIH RePORTER |
What this research studies
This research investigates the role of methionine, a sulfur-containing amino acid, in regulating cell growth and survival. It aims to understand how methionine and its metabolite, S-adenosylmethionine, influence critical cellular pathways in response to metabolic changes. By employing genetics and biochemistry techniques, the study will explore how these compounds affect signaling processes, gene expression, and modifications on chromatin. The findings could provide insights into the mechanisms underlying aging and age-related diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the effects of metabolism on aging and those with age-related conditions.
Not a fit: Patients with acute metabolic disorders unrelated to aging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing aging and related diseases by targeting metabolic pathways.
How similar studies have performed: Previous research has shown promising results in understanding metabolic signals and their impact on cellular processes, suggesting that this approach could yield valuable insights.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Tu, Benjamin P — Ut Southwestern Medical Center
- Study coordinator: Tu, Benjamin P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.