How methionine affects cancer and aging
Official title: The regulation of cancer and aging by methionine
Funded at University of Wisconsin-Madison · NIH-11046653 · Data updated 2026-11-12
This study is looking at how cutting back on a certain amino acid called methionine in our diets might help improve health and slow down aging, especially in relation to cancer, and it's aimed at finding new ways to treat age-related diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | July 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $606,677 |
| NIH project number | 5R01AG084156-03 |
| Project ID | NIH-11046653 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who are at risk for age-related diseases, particularly cancer.
✕Less likely to help
Patients who are younger than 21 or those with non-age-related health issues may not benefit from this research.
What this research studies
This research investigates the role of methionine, an amino acid, in the development of cancer and the aging process. By focusing on how dietary methionine restriction can influence health and longevity, the study aims to uncover mechanisms that could lead to new treatments for age-related diseases, particularly cancer. The research will utilize animal models to explore the effects of methionine on cancer progression and overall health as individuals age, with the goal of translating these findings into potential human therapies.
Why it matters
Potential benefit: If successful, this research could lead to new dietary interventions that improve health and longevity while reducing cancer risk in older adults.
How similar studies have gone: Previous studies have shown that dietary interventions like methionine restriction can positively impact health and longevity in animal models, suggesting potential for success in this area.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Lamming, Dudley William — University of Wisconsin-Madison
- Study coordinator: Lamming, Dudley William
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.