How methamphetamine affects immune response in people with HIV
Methamphetamine Activation of Inflammasome and Altered immunity in HIV (MAIA) Study
This study is looking at how using methamphetamine affects the immune system of people living with HIV, to see if it causes inflammation and other issues, even for those on treatment, so we can find better ways to help improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11062197 on NIH RePORTER |
What this research studies
This research investigates the impact of methamphetamine use on the immune system of individuals living with HIV. It aims to understand how methamphetamine activates specific immune pathways that may lead to inflammation and immune dysfunction, even in patients receiving antiretroviral therapy. By analyzing blood samples from patients who use methamphetamine and those who do not, the study will explore the biological mechanisms behind these effects. The goal is to identify potential targets for improving treatment outcomes in this high-risk population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are also methamphetamine users.
Not a fit: Patients who do not have HIV or do not use methamphetamine may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for individuals with HIV who also use methamphetamine, potentially enhancing their immune response and overall health.
How similar studies have performed: Previous research has shown that addressing inflammation and immune dysfunction in HIV can lead to better treatment outcomes, suggesting that this approach may be promising.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Pereira Ribeiro, Susan — Emory University
- Study coordinator: Pereira Ribeiro, Susan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.