How methamphetamine affects immune response in people with HIV
Official title: Methamphetamine Activation of Inflammasome and Altered immunity in HIV (MAIA) Study
Funded at Emory University · NIH-11062197 · Data updated 2026-11-12
This study is looking at how using methamphetamine affects the immune system of people living with HIV, to see if it causes inflammation and other issues, even for those on treatment, so we can find better ways to help improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 30, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $740,880 |
| NIH project number | 1R01DA062380-01 |
| Project ID | NIH-11062197 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV who are also methamphetamine users.
✕Less likely to help
Patients who do not have HIV or do not use methamphetamine may not benefit from this research.
What this research studies
This research investigates the impact of methamphetamine use on the immune system of individuals living with HIV. It aims to understand how methamphetamine activates specific immune pathways that may lead to inflammation and immune dysfunction, even in patients receiving antiretroviral therapy. By analyzing blood samples from patients who use methamphetamine and those who do not, the study will explore the biological mechanisms behind these effects. The goal is to identify potential targets for improving treatment outcomes in this high-risk population.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for individuals with HIV who also use methamphetamine, potentially enhancing their immune response and overall health.
How similar studies have gone: Previous research has shown that addressing inflammation and immune dysfunction in HIV can lead to better treatment outcomes, suggesting that this approach may be promising.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Pereira Ribeiro, Susan — Emory University
- Study coordinator: Pereira Ribeiro, Susan
Related research
Other NIH-funded projects on the same topics.
-
Administrative and Engagement Core for Breast Cancer Breakthrough in Kenya
A national effort in Kenya to speed up how we screen for breast cancer and connect women to treatment, using teamwork across institutions.
-
Collaborative research program to advance patient care
A multi-project research effort at Emory University aims to push forward medical knowledge that could help people with illnesses in the future.
-
Project-003: A multi-partner research program at Emory University
A multi-faceted NIH grant at Emory University aims to advance understanding in a focused area over several years to benefit patients with diseases or conditions connected to the research.
-
Project-002: advancing patient care through coordinated research at Emory
A multi-project NIH grant at Emory aims to translate findings into better care for people with a health condition by coordinating research efforts across teams.
-
Project-006: A Multidisciplinary Emory Initiative to Advance Medical Understanding
A multi-project NIH grant at Emory University aims to push forward medical knowledge in areas that could eventually help patients.
-
Project-005: A multi-component research effort at Emory University
A multi-part NIH grant from Emory University aims to advance understanding in a specific health area over several years with potential patient benefits in the future.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.