How metals in human milk affect childhood growth
Metal Impacts on miRNAs in Human Milk and Contributions to Early Childhood Growth
This study is looking at how being around certain metals might change the tiny molecules in breast milk that can affect how babies grow and their chances of becoming overweight, especially in rural areas.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-11130493 on NIH RePORTER |
What this research studies
This research investigates how exposure to metals can influence the levels of microRNAs in human milk and their subsequent impact on early childhood growth and obesity. It focuses on understanding the mechanisms by which these environmental factors affect breastfeeding and metabolic programming in infants. The study aims to identify specific microRNAs that may be altered by metal exposure and how these changes can contribute to accelerated growth and adiposity in children, particularly in rural populations. By analyzing human milk samples and their effects on infant development, the research seeks to uncover critical insights into preventing obesity from an early age.
Who could benefit from this research
Good fit: Ideal candidates for this research include breastfeeding mothers living in rural areas who may have been exposed to environmental metals.
Not a fit: Patients who are not breastfeeding or those living in urban areas with minimal exposure to environmental metals may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing childhood obesity by understanding the role of environmental factors in early growth.
How similar studies have performed: Other research has shown that environmental exposures can significantly impact childhood obesity, suggesting that this approach may yield valuable insights.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Howe, Caitlin Grace — Dartmouth College
- Study coordinator: Howe, Caitlin Grace
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.