How metabolism affects embryo development
Functional contribution of Metabolism in embryonic development
['FUNDING_R21'] · BROWN UNIVERSITY · NIH-10701781
This study is looking at how a special way of processing energy in cells helps sea urchin embryos grow and develop, using cool imaging tools to see these changes in action.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BROWN UNIVERSITY (nih funded) |
| Locations | 1 site (PROVIDENCE, UNITED STATES) |
| Trial ID | NIH-10701781 on ClinicalTrials.gov |
What this research studies
This research investigates the role of aerobic glycolysis, a unique metabolic process, in the development of embryos. By using sea urchin embryos as a model, the researchers aim to visualize metabolic changes in real-time during embryogenesis. They will employ advanced imaging techniques to observe how these metabolic dynamics influence cell signaling and differentiation at critical stages of development. The goal is to understand how metabolism contributes to the proper formation and function of cells in embryos.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the biological mechanisms of embryonic development or those affected by developmental disorders.
Not a fit: Patients with fully developed embryos or those not facing developmental issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of embryonic development and potentially lead to new strategies for addressing developmental disorders.
How similar studies have performed: Other research has shown that metabolic processes play a significant role in cellular functions, suggesting that this approach could yield valuable insights.
Where this research is happening
PROVIDENCE, UNITED STATES
- BROWN UNIVERSITY — PROVIDENCE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YAJIMA, MAMIKO — BROWN UNIVERSITY
- Study coordinator: YAJIMA, MAMIKO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.