How metabolic signals and the circadian clock affect protein synthesis
Regulation of protein synthesis by metabolic signals and the circadian clock
This study looks at how different signals like light and temperature affect how plants make proteins, using a small plant called Arabidopsis, to help us understand how cells grow and develop better.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tennessee Knoxville NIH-funded |
| Lab location | 1 site (Knoxville, United States) |
| Project ID | NIH-10797235 on NIH RePORTER |
What this research studies
This research investigates how various signals, such as light, temperature, and metabolic markers, influence the process of protein synthesis in cells. By studying the plant Arabidopsis thaliana, researchers aim to understand the role of a specific signaling pathway that regulates the loading of mRNA onto ribosomes, which is crucial for protein production. The project employs advanced molecular and biochemical techniques to explore how these signals are integrated and their effects on cellular functions. This could provide insights into the fundamental processes that govern cell growth and development.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the biological mechanisms of growth and development, particularly in relation to metabolic health and circadian rhythms.
Not a fit: Patients with conditions unrelated to metabolic signaling or circadian rhythms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of cellular processes that may enhance agricultural productivity and health.
How similar studies have performed: Other research has shown promising results in understanding metabolic signaling and circadian rhythms, indicating that this approach is grounded in established scientific principles.
Where this research is happening
Knoxville, United States
- University of Tennessee Knoxville — Knoxville, United States (Active)
Researchers
- Principal investigator: Von Arnim, Albrecht G. — University of Tennessee Knoxville
- Study coordinator: Von Arnim, Albrecht G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.