How menopause and hormone therapy affect brain health in breast cancer survivors
Brain Health in Breast Cancer Survivors: Interaction of Menopause and Endocrine Therapy
This study is looking at how hormone therapy for breast cancer affects brain health and thinking skills in women who have survived the disease, especially considering how menopause and changes in estrogen levels play a role.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10656425 on NIH RePORTER |
What this research studies
This research investigates the impact of endocrine therapy on brain health in breast cancer survivors, particularly focusing on how changes in estrogen levels due to treatment and menopause interact. By utilizing advanced neuroimaging techniques, the study aims to understand the cognitive effects of hormone receptor positive breast cancer treatments. The research will involve a cross-sectional analysis to assess brain activity and cognitive function in relation to menopausal status and hormone therapy. This approach seeks to clarify the inconsistent findings from previous studies regarding cognitive health in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who are breast cancer survivors and are currently undergoing or have undergone endocrine therapy.
Not a fit: Patients who are not breast cancer survivors or those who have not received endocrine therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cognitive health in breast cancer survivors undergoing hormone therapy.
How similar studies have performed: While there have been studies on the effects of endocrine therapy on cognitive health, this research aims to provide a novel perspective by specifically examining the interaction with menopausal status using advanced imaging techniques.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Van Dyk, Kathleen — University of California Los Angeles
- Study coordinator: Van Dyk, Kathleen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.