How menopause affects eye pressure and glaucoma risk
Impact of Menopause on the Aqueous Outflow Pathway
This study is looking at how menopause might affect the risk of developing glaucoma, a serious eye condition that can lead to blindness, by exploring how changes in hormone levels during this time could impact eye pressure and fluid drainage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10916245 on NIH RePORTER |
What this research studies
This research investigates the relationship between menopause and the risk of developing glaucoma, a leading cause of blindness. It focuses on how changes in estrogen levels during menopause may influence intraocular pressure (IOP) and aqueous outflow resistance in the eye. By examining the effects of menopause on the trabecular meshwork, which regulates fluid drainage from the eye, the study aims to uncover mechanisms that could lead to increased glaucoma risk in women. The research employs various methodologies, including assessments of protein expression and biomechanical properties of eye tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women or those experiencing early menopause who are at risk for glaucoma.
Not a fit: Patients who are premenopausal or have no risk factors for glaucoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of glaucoma risk in postmenopausal women.
How similar studies have performed: Previous research has indicated a link between hormonal changes and glaucoma risk, suggesting that this investigation builds on established findings rather than exploring entirely novel territory.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Feola, Andrew J — Emory University
- Study coordinator: Feola, Andrew J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.