How Medicare's bundled payment program affects sepsis care for people with Alzheimer's and related dementias

The Impact of the Bundled Payment for Care Improvement Advanced on Outcomes for Patients with Sepsis

['FUNDING_R01'] · BROWN UNIVERSITY · NIH-11262209

Looks at whether Medicare's bundled payment program changes sepsis care and recovery for older adults, including people with Alzheimer's disease and related dementias.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBROWN UNIVERSITY (nih funded)
Locations1 site (PROVIDENCE, UNITED STATES)
Trial IDNIH-11262209 on ClinicalTrials.gov

What this research studies

You would learn how hospitals that joined Medicare’s Bundled Payment for Care Improvement Advanced (BPCI-A) program handled sepsis differently than hospitals that did not. The researchers use Medicare claims and hospital data to compare 90-day spending, where patients go after discharge, and rates of complications or readmissions. They focus on older patients and specifically those with Alzheimer's disease and related dementias to see if outcomes are better or worse under bundled payments. The team compares trends over time to estimate how the payment program affected care and recovery.

Who could benefit from this research

Good fit: The most relevant people are Medicare beneficiaries hospitalized with sepsis, especially older adults who also have Alzheimer's disease or related dementias.

Not a fit: Younger people, those not covered by Medicare, or people without sepsis would not be affected by this specific analysis.

Why it matters

Potential benefit: If successful, this work could encourage hospital and payment changes that reduce complications, improve recovery after sepsis, and lower costs for older adults with dementia.

How similar studies have performed: Previous studies of bundled payment programs have sometimes lowered spending but shown mixed effects on patient outcomes, and applying this approach specifically to sepsis in people with dementia is relatively new.

Where this research is happening

PROVIDENCE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer's Disease and its related dementias, Alzheimer's disease and related dementia, Alzheimer's disease and related disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.