How medical cannabis affects physical and mental health

Cannabis effects on physical and mental health in medical cannabis patients

NIH-funded research Rutgers Biomedical and Health Sciences · NIH-11314516

This project looks at whether medical cannabis leads to problematic patterns of use and how tolerance and withdrawal relate to physical and mental health in adult medical cannabis patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers Biomedical and Health Sciences NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project IDNIH-11314516 on NIH RePORTER

What this research studies

You would be part of research that adapts prescription-medication diagnostic ideas to medical cannabis so doctors can tell expected medication effects from a harmful pattern of use. The team will collect symptom reports, medical history, alcohol co-use information, and biological markers and follow patients over time to see who develops signs of problematic use. They will focus on tolerance and withdrawal symptoms and compare those with behaviors like impaired control or continued use despite problems. Findings will be used to improve how clinicians identify and monitor patients at higher risk for cannabis use disorder while using medical cannabis.

Who could benefit from this research

Good fit: Adults (18+) who use medical cannabis regularly or who are concerned about tolerance, withdrawal, or cannabis-related problems would be ideal candidates.

Not a fit: People under 18, recreational-only cannabis users, or those unwilling to provide follow-up information or samples are unlikely to benefit directly from participating.

Why it matters

Potential benefit: If successful, this work could help clinicians spot and prevent problematic cannabis use in medical cannabis patients and guide safer monitoring and dosing.

How similar studies have performed: Large surveys have shown a portion of medical cannabis users meet CUD criteria, but applying DSM-5 prescription-medication approaches to medical cannabis is relatively new and not yet widely tested.

Where this research is happening

Newark, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.