How maternal stress during pregnancy affects child brain development

Psychosocial unpredictability during pregnancy and offspring neurodevelopment: Uncovering mechanisms and sensitive windows in utero

['FUNDING_CAREER'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-10904930

This study is looking at how stress that moms experience during pregnancy might affect their baby's brain development, with the goal of finding ways to help reduce any risks for future mental health issues in kids.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorNEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10904930 on ClinicalTrials.gov

What this research studies

This research investigates how unpredictable psychosocial stress experienced by mothers during pregnancy can influence the neurodevelopment of their children. It focuses on understanding the biological mechanisms that connect maternal stress to potential psychiatric issues in offspring. By utilizing advanced techniques such as fetal brain imaging and monitoring maternal-infant cortisol levels, the study aims to identify critical periods during pregnancy when the fetus is most vulnerable to stress. The findings could help in developing interventions to mitigate these risks.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant individuals experiencing significant psychosocial stress, particularly those from historically minoritized backgrounds.

Not a fit: Patients who are not pregnant or those who do not experience psychosocial stress may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to strategies that reduce the risk of psychiatric disorders in children by addressing maternal stress during pregnancy.

How similar studies have performed: Previous research has shown that maternal stress can significantly impact child development, indicating that this approach has a foundation in established findings.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.