How maternal stress and oxidative stress affect child asthma risk
Associations among maternal lifetime psychosocial stress, prenatal systemic and placental oxidative stress mixtures, and child asthma
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11070297
This study looks at how a mother's stress throughout her life might affect her children's chances of developing asthma, especially in families from lower-income BIPOC communities, and aims to find out how these experiences can impact kids' lung health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11070297 on ClinicalTrials.gov |
What this research studies
This research investigates how a mother's lifetime experiences of stress and the resulting oxidative stress may influence the development of asthma in her children. It focuses on understanding the biological mechanisms that link maternal trauma to respiratory health outcomes in children, particularly among lower-income BIPOC populations. By examining the role of oxidative stress and its impact on fetal development, the study aims to identify potential biomarkers that could help explain health disparities in asthma prevalence. The research employs a combination of cohort studies and biological assessments to gather data on these complex interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women, especially those from lower-income BIPOC backgrounds who have experienced significant life stressors.
Not a fit: Patients who are not pregnant or those without a history of significant psychosocial stress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for asthma in children, particularly in vulnerable populations.
How similar studies have performed: Previous research has shown promising results in understanding the links between maternal stress and child health outcomes, but this specific approach focusing on oxidative stress in BIPOC populations is relatively novel.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CARROLL, KECIA NICOLE — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: CARROLL, KECIA NICOLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.