How maternal obesity affects pregnancy and future health in women
Official title: Lifecycle of obesogenic gender behaviors and cardiometabolic disease in women
Funded at Colorado State University · NIH-10990327 · Data updated 2026-11-12
This study looks at how being overweight during pregnancy can affect both the mom and baby, especially regarding issues like high blood pressure, and it explores whether improving gut health through diet or probiotics can help make things better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $377,959 |
| NIH project number | 1R01HL165467-01A1 |
| Project ID | NIH-10990327 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant women who are experiencing obesity and related complications such as preeclampsia.
✕Less likely to help
Patients who are not pregnant or do not have obesity-related complications may not benefit from this research.
What this research studies
This research investigates the impact of maternal obesity on pregnancy outcomes, particularly focusing on conditions like preeclampsia. It explores how the maternal gut microbiome and dietary habits contribute to inflammation and complications during pregnancy. By using a mouse model, the study aims to understand the mechanisms behind these effects and whether probiotic supplementation can improve outcomes. The findings could provide insights into how maternal health influences both immediate pregnancy complications and long-term cardiometabolic health in offspring.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing pregnancy complications related to obesity, benefiting both mothers and their children.
How similar studies have gone: Previous research has shown promising results in understanding the role of the gut microbiome in pregnancy outcomes, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Colorado State University
Fort Collins, United States Active
Researchers
- Principal investigator: Sones, Jennifer Liford — Colorado State University
- Study coordinator: Sones, Jennifer Liford
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.