How maternal health affects newborn immunity to COVID-19
Investigating the role of maternal-fetal crosstalk on neonatal immunity in COVID-19 infection or vaccination in pregnancy
This study looks at how a mother's COVID-19 infection or vaccination can affect her baby's immune system, helping us understand how antibodies are passed from mom to baby and how this might protect them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11005739 on NIH RePORTER |
What this research studies
This research investigates how maternal infection or vaccination against COVID-19 influences the immune responses of newborns. It focuses on the transfer of antibodies from mother to fetus and how this may protect or affect the infant's immune system. By analyzing samples from pregnant women and their infants, the study aims to understand the specific immune responses that develop in newborns as a result of maternal COVID-19 exposure. The findings could help optimize vaccination strategies for pregnant women to enhance protection for both mothers and their babies.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women who have been infected with COVID-19 or vaccinated against it, as well as their newborns.
Not a fit: Patients who are not pregnant or whose infants are older than 4 weeks may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies for pregnant women, enhancing immunity in newborns against COVID-19.
How similar studies have performed: Other research has shown promising results regarding maternal vaccination and its effects on neonatal immunity, indicating that this approach is building on established findings.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Gaw, Stephanie Lina — University of California, San Francisco
- Study coordinator: Gaw, Stephanie Lina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.